This gene is really a member of the SUMO gene family members. This relatives of genes encode compact ubiquitin-related modifiers which might be hooked up to proteins and Manage the focus on proteins' subcellular localization, security, or action. The protein explained With more info this file is found in the cytoplasm and particularly modifies IKBA, resulting in detrimental regulation of NF-kappa-B-dependent transcription of your IL12B gene.
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